Thiazine 100 Injection
Thiazine 100 Injection is a potent sedative, analgesic, and muscle relaxant for use in horses, cattle, sheep, goats, and dogs.
It contains Xylazine Hydrochloride 100 mg/mL, a reliable alpha-2 adrenergic agonist that induces calmness, pain relief, and muscle relaxation.
It is widely used in veterinary anesthesia protocols as a premedicant, restraint aid, or minor surgical sedative.
Active Constituent (per mL)
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Xylazine (as hydrochloride) – 100 mg
Pharmacological Action
Xylazine acts centrally on alpha-2 adrenergic receptors to inhibit norepinephrine release, resulting in sedation, analgesia, and skeletal muscle relaxation.
It also reduces stress-related physiological responses, making it effective for handling or minor procedures.
Indications
✅ Sedation and restraint during diagnostic or minor surgical procedures
✅ Analgesia for short-term pain management
✅ Muscle relaxation during operations or examinations
✅ Premedication prior to general anesthesia
✅ Control of colic pain in horses
Target Species
🐎 Horses
🐄 Cattle
🐑 Sheep
🐐 Goats
🐕 Dogs
Dosage & Administration
Route: Intramuscular (IM) or Slow Intravenous (IV) Injection
| Species | IM Dose | IV Dose | Onset (min) | Duration (min) |
|---|---|---|---|---|
| Horses | 0.5–1.1 mg/kg | 0.3–0.5 mg/kg | 3–5 | 30–60 |
| Cattle | 0.05–0.2 mg/kg | 0.02–0.1 mg/kg | 5–10 | 30–90 |
| Dogs | 1–2 mg/kg | 0.5–1 mg/kg | 5–10 | 20–40 |
(Adjust dosage according to species, temperament, and procedure type.)
Precautions
⚠️ Use only under veterinary supervision.
⚠️ Avoid in late pregnancy, heart disease, or respiratory distress.
⚠️ Reduce dose when combined with anesthetics (e.g., ketamine).
⚠️ Do not use in dehydrated, shocked, or severely stressed animals.
⚠️ Ensure animals are kept in quiet surroundings post-administration.
Antidote (Reversal Agent)
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Yohimbine or Atipamezole may be used to reverse sedation and cardiovascular effects.
Storage
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Store below 25°C
-
Protect from light and freezing
Key Benefits
✔ Provides effective sedation and pain relief
✔ Reduces animal stress and movement
✔ Facilitates safe handling and minor procedures
✔ Rapid onset and predictable recovery
✔ Compatible with anesthetic combinations
Xylazine 100 mg/mL (as hydrochloride)