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Naquasone (Tri-Dex) is a combination therapy containing a diuretic and a corticosteroid (Dexamethasone).
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It is used in horses to manage edema, inflammation, and fluid retention associated with various conditions, including respiratory disease, musculoskeletal issues, and recovery after exertion.
Composition
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Triamterene or related thiazide-type diuretic component (for controlled fluid removal).
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Dexamethasone (potent corticosteroid, anti-inflammatory).
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Sterile injectable aqueous base.
Pharmacological Action
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Diuretic effect: Promotes elimination of excess fluid, reducing tissue swelling and edema.
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Anti-inflammatory action: Corticosteroid reduces inflammation, pain, and allergic reactions.
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Synergistic effect: Diuretic + steroid combination provides both rapid relief of swelling and improved recovery.
Indications
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Edema (respiratory tract, legs, or systemic).
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Allergic or inflammatory conditions.
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Musculoskeletal inflammation with fluid retention.
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Management of respiratory distress linked to edema.
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Supportive therapy in racing or performance horses.
Dosage & Administration
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IV or IM injection under veterinary supervision.
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Dosage varies depending on severity and weight:
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Typical equine range: 0.5 – 1 mL/45–90 kg body weight, adjusted as per condition.
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Short-term use only; avoid prolonged corticosteroid administration without monitoring.
Benefits
✔ Rapid reduction of swelling and edema
✔ Relieves inflammation and pain
✔ Improves breathing in respiratory edema
✔ Supports musculoskeletal recovery in performance horses
✔ Combination therapy reduces need for higher steroid doses
Storage
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Store below 25°C, away from light.
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Keep vial sealed and sterile.
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For veterinary use only.